Adaptive Immunity

Microscopy

Note Packet

Lesson

Topic

Statement(s) and Objective(s)

Activities

1	Sense of Scale		Biology as an observational science The Big and the Small reading questions The Big and the Small debrief Brush with Nature Directions Brush with Nature student template A&B: Art and Microscopy
2	Types of Microscopes	1.2.U4: Electron microscopes have a much higher resolution than light microscopes. Define resolution. Compare the functionality of light and electron microscopes. 1.2.NOS: Developments in scientific research follows improvements in apparatus- the invention of the electron microscopes led to greater understanding of cell structure. With reference to a specific example, explain how an improvement in apparatus allowed for greater understanding of cell structure.	A&B: World’s Within A&B: View to a Cell NABT: The Dawn of the Microscope Improved technology in observations Technology begets discovery Debrief slides Types of microscopes station 1 notes AB: This Podcast Will Kill You discovery of micros and development of microscope
3	Use of Microscopes	1.1.S1: Use of a light microscope to investigate the structure of cells and tissues.(Practical 1) Label the names of parts of the microscope. Define magnification. Given the magnification of the ocular and objective lenses, calculate the total microscope magnification. Demonstrate how to focus the microscope on a sample.	Virtual lab Convert Cell Phones into “Cell Cams” Magnification station 2 Resolution station 3 Resolution images for station Parts of the microscope station 4 Labels for microscope at station 4 Microscope diagram to label Focusing station 5 Microscope Basics CFU
4	Determining the Field of View	1.1.S1: Use of a light microscope to investigate the structure of cells and tissues.(Practical 1) Measure the field of view diameter of a microscope under low power. Calculate the field of view diameter of a microscope under medium or high power.	FOV on low power station 6 Calculating FOV on high power station 7 FOV CFU
5	Estimating Sample Size	1.1.S1: Use of a light microscope to investigate the structure of cells and tissues.(Practical 1) Estimate the size of a sample in the microscope field of view.	Estimating sample size station 8 Estimating sample size CFU
6	Drawing Cell Structures	1.1.S2: Drawing cell structures as seen with the light microscope . Demonstrate how to draw cell structures seen with a microscope using sharp, carefully joined lines and straight edge lines for labels.	Drawing Cells directions Drawing from observations lab Drawing from Gizmos Sample drawing 1 Sample drawing 2 Sample drawing 3
7	Calculation of Drawing Size	1.1.S3: Calculation of the magnification of drawings and the actual size of structures and ultrastructures shown in drawings or micrographs. Define micrograph. State why the magnification of a drawing or micrograph is not the same as the magnification of the microscope. Use a formula to calculate the magnification of a micrograph or drawing. If given the magnification of a micrograph or drawing, use a formula to calculate the actual size of a specimen.	Drawing magnification notes Drawing magnification CFU 1 Drawing magnification CFU 2 Organisms and cells cards (table groups work together to calculate magnification of each image) Individual practice prompts More practice whiteboards Self-quiz Answers to practice problems in notes A&B: make a hanging model of one of the organisms from the organisms can cells cards and then calculate the magnification of your model. (from HHMI)
8	Wrap Up and Review		Group review of microscopy Stations review Final knowledge audit Unit quizlet set Kahoot review Quizizz review 1 page summary